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Abbott Clinical Research

Lab Results - What they all mean!

When you screen and do a study, you will have many procedures done to determine if you are healthy.  Here are some of the most common tests done with links for additional information primarily through wikipedia.  I'm working on this!  Please note that any information provided is not to be used as medical advice!

 

 

Genotyping

Basically the genetic makeup of a person.  Drug companies may add this test in order to determine why some people react to a drug in a particular way when others don't. 

 

The test is usually one tube of blood.

HIV/AIDS

Human immunodeficiency virus (HIV) is a virus that can lead to acquired immunodeficiency syndrome (AIDS).  All clinics will screen for HIV and AIDS.  These tests must be negative for you to participate in a healthy Phase 1 trial. 

 

The test is done via blood sample. 

Electrocardiogram

Electrocardiogram (ECG/EKG) is a test that measures the electrical activity of the heart. 

 

The test is done using an ECG machine with 10 to 12 leads attached to your chest and limbs via sticky pads. 

Vital Signs

Vitals signs measures your blood pressure (systolic and diastolic), body temperature, pulse rate and respirations

 

The test is done with a blood pressure machine and temperature probe.  Respirations are counted manually. 

Hepatitis A, B and C

Hepatitis is an inflammatory virus of the liver.  It is divided into several categories but the main 3 are A, B and C.  Most clinics only test for B and C.  If you have had a vaccination for either of the infections, you should inform the clinic of when the vaccination was done.  Some studies will not allow subjects with certain vaccinations. 

 

The test is done via blood sample. 

BMI/IBW

Body Mass Index Calculator/Ideal Body Weight Calculator.  Some studies use the BMI scale while others use the IBW scale. 

 

Urinalysis

A Urinalysis (UA) tests for illicit drugs, alcohol, cotinine and other factors. 

 
Drugs:
Alcohol  
Amphetamine  
Barbiturates  
Benzodiazepines  
Cannabinoids  
Cocaine Metabolite  
Cotinine  
Opiates  
 
Other Tests:
Amorth Sediment  
Bacteria  
Casts  
Crystals  
Epithelial Cells  
Glucose Urine  
Ketones Urine  
Mucus  
Myoglobin  
Nitrate  
Occult Blood  
PH Urine  
Protein Urine  

Red Blood Cells

RBC

 
Sp Gravity  
Urobilinogen  

White Blood Cells

WBC

 

 

The test is done with approximately 40 ML of urine collected into a sterile specimen container. 

 

Blood Draw

Having your blood drawn (phlebotomy) is the primary source of information that is collected during a study.   The following is a list of general tests that are usually done.  There may be additional tests done for study specific requirements.  

 

Alanine Aminotransferase

ALT

Liver

 

Albumin

ALB

 

Alkaline Phosphatase

ALK PHOS

 

Aspartate Aminotransferase

AST

 
Basophils  

Blood Urea Nitrogen

BUN

 
Calcium  

Carbon Dioxide

CO2

 

Chloride

Cl

 

Cholesterol

 

Creatine Kinase

CK

 

Eosinophils

 

Gamma-Glutamyl Transferase

GGT

 

Glucose Blood

Blood Sugar

 

Hematocrit

Hct, Crit

 

Hemoglobin

Hgb, Hb

 
Hep B S Ag  
Hep C Ab  

High-density lipoprotein cholesterol

HDL

 
HIV 1 Ab  
HIV 2 Ab  

Lactate Dehydrogenase

LDH

 

Low-density lipoprotein cholesterol

LDL

 
Lymphocytes  

Magnesium

Mg

 
Mean Corpuscular Hemoglobin

MCH

 

Mean Corpuscular Hemoglobin Concentration

MCHC

 

Mean Corpuscular Volume

MCV

 

Monocytes

 
Neutrophil  
Plateletes  

Phosphate

Phosphorus, P, PO4

 

Potassium

K

 

Red blood Cell Count

RBC

 

Sodium

Na

 

Total Bilirubin

 

Total Protein

TP

 

Triglycerides

TG, TRIG

 

Uric Acid

Urate

 

White Blood Cell Count

WBC

 

The test is typically done using a needle with a barrel and vacutainers.  The needle is inserted into a vein and the required amount of tubes are inserted one at a time.  Once the tubes are filled, the needle is removed and gauze is placed over the hole.  Hold the gauze with firm pressure for 5 to 10 minutes or until the hole is sealed and has stopped bleeding.  

 

Abbott Clinical Research

 

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